What is the CPT Code for a CBC with Differential?

A Complete Blood Count (CBC) with Differential is one of the most common lab tests ordered by physicians. It measures the levels of different blood components such as red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The “differential” specifically breaks down the types of white blood cells, providing critical insights for diagnosing infections, anemia, and other conditions. For providers and billing teams, accurate coding of this test is crucial to ensure proper reimbursement and avoid claim denials.

CPT Code for CBC with Differential

The CPT code for a Complete Blood Count (CBC) with Differential is:

• 85025 – Blood count, complete (CBC), automated, and automated differential WBC count

This is the most commonly used code when both the complete blood count and the differential white blood cell count are performed.

In comparison:

• 85027 – CBC without differential

• 85004 – Automated differential WBC count only

Correctly identifying whether the test includes the differential ensures accurate claim submission.

Why Accurate Coding for CBC with Differential Matters

Submitting the wrong code can cause:

• Claim denials or reimbursement delays

• Compliance risks with payer guidelines

• Revenue loss for providers

Since CBC tests are ordered frequently, even small coding errors can lead to significant financial impact over time.

How EZ Settle Solutions Helps with Laboratory Billing

At EZ Settle Solutions, we provide tailored billing solutions for practices, laboratories, and clinics. Our experts ensure accurate coding for commonly ordered procedures like CBC with Differential, helping providers maximize reimbursements and reduce claim denials.

Our services include:

• Medical Billing and Coding to ensure every claim is accurate and compliant

• Revenue Cycle Management in Medical Billing to improve cash flow and reduce denials

• Services designed for healthcare practices across specialties

For official coding updates, providers can also review the AMA CPT® coding resource.

Final Thoughts

The CPT code 85025 is used for a CBC with Differential, a test that plays a vital role in patient diagnosis and care. Choosing the correct CPT code not only ensures compliance but also prevents claim rejections and protects your revenue. With the right billing partner like EZ Settle Solutions, healthcare providers can focus on patient care while we manage coding accuracy and reimbursement efficiency.