What Are the CPT Codes Commonly Used for GI Procedures?

Gastrointestinal (GI) procedures are critical to diagnosing and treating digestive system conditions. From colonoscopies to capsule endoscopies, these services must be correctly coded for accurate billing and insurance reimbursement. That’s where CPT (Current Procedural Terminology) codes come in. These standardized codes simplify the billing process and minimize claim denials. At EZ Settle Solutions, we help GI practices navigate this complexity with precise and compliant medical billing services tailored to their needs.

Common CPT Codes in GI Procedures

Here are several frequently used CPT codes associated with GI diagnostics and treatments:

• 45378 – Diagnostic colonoscopy
• 43235 – Upper GI endoscopy (EGD), diagnostic
• 45380 – Colonoscopy with biopsy
• 43239 – EGD with biopsy
• 91110 – Capsule endoscopy
• 44388 – Ileoscopy via stoma

Each code reflects a unique service, and additional modifiers may be required based on the complexity or multiple procedures performed during a single visit.

To explore a specific procedure in more detail, read our guide on the Upper GI Endoscopy Procedure.  For the official CPT code listing and updates, visit the AMA CPT Code Set.

Why CPT Coding Accuracy Matters in GI Billing

GI practices often perform multifaceted procedures that combine diagnostics, biopsies, and therapeutic interventions. Failing to apply the correct CPT codes can result in revenue loss, claim rejections, or compliance issues. Our Gastroenterology Medical Billing services ensure your claims are clean, accurate, and aligned with payer-specific requirements. We eliminate guesswork and optimize your practice’s cash flow by managing coding and billing complexities.

Revenue Cycle Management Support for GI Practices

At EZ Settle Solutions, we go beyond coding. Our complete Revenue Cycle Management (RCM) services track every step from patient eligibility to final payment. With a proactive approach to claim submission, denial management, and payment posting, we help practices maintain financial health while focusing on patient care. Curious how the RCM workflow impacts GI billing success? Learn more in our detailed guide: What is the Revenue Cycle Management Process in Medical Billing?

Final Thoughts

Understanding the right CPT codes for GI procedures is essential for accurate billing and reimbursement. Whether you’re coding for a routine colonoscopy or a more advanced GI study, having a partner like EZ Settle Solutions ensures your practice stays compliant, profitable, and stress-free. Ready to optimize your GI billing process? Request a demo and see how we can simplify your revenue cycle.